Research · Setup in 10 min· Setup Pass

Set up OpenEvidence for supplement research in 10 minutes

Configure this clinical AI search engine to find human evidence for or against a supplement.

You need to check the evidence for a supplement, but PubMed is noisy and general search is full of affiliate marketing. This setup configures OpenEvidence to find human trial data for a specific compound, fast.

Before you start

• An OpenEvidence account
• The name of a supplement to research
• 10 quiet minutes

The steps

1. 01

   Start a new question

   From the dashboard, start a new question. Use the PICO (Population, Intervention, Comparison, Outcome) framework to structure your query. For example: "In adult women [Population], does creatine monohydrate [Intervention] compared to placebo [Comparison] improve cognitive function [Outcome]?"

2. 02

   Synthesize the evidence

   OpenEvidence will return a direct answer and a list of sources. Use the "Synthesize" button to generate a summary of findings from the top papers. This gives you a quick overview of the consensus, if any.

3. 03

   Filter for human trials

   In the left-hand sidebar, find the "Study Type" filter. Select "Human" to exclude animal or in-vitro studies. This is the most important step for finding relevant data for personal health or client protocols.

4. 04

   Review the Ledger

   Examine the "Ledger" view. This table extracts key data points like population, dosage, and outcomes from each study. Use this to create the Research layer of your 3-Layer Method, noting the exact dosages and effects reported in the literature.

5. 05

   Export for your notes

   Use the export function to save the synthesis and list of sources. For practitioners, this provides quote-grade answers for client conversations and case notes. For individuals, it creates a clean record of the evidence you based your decision on.